First, you need to open the Programs and Features in Control Panel. Once opened, scroll down to Skype for Business and click Uninstall. You will be prompted with a message saying that you are about to uninstall Skype for Business. Click Yes. The process should take only a few minutes.

It sounds like your Skype for Business window is popping up because you have it open and minimized. The way to get rid of the pop-up is to close the Skype for Business window.

To disable Skype for Business, navigate to the Office 365 admin center and select Skype for Business.Under Exchange Online Protection, click on View Details.Select Disable Product.

If you’re using Windows 7, 8, or 10, you can use the Group Policy Editor to remove Skype for Business. You can also use the registry editor to remove it.If you’re using Windows XP or Vista, then you’ll need to manually edit the registry.

Skype is a communication service that you can use to chat with friends and family. If you want to delete Skype, you need to uninstall the program through Control Panel or by using the Add or Remove Programs feature in Control Panel. You may also need to delete the Skype folder from your hard drive.